2008 Toronto Batting, Pitching and Fielding Statistics |
| 94-68, 2nd in American League East |
| Manager: John Gibbons (94-68) |
| Ballpark: Rogers Centre |
| Roster |
| Team Batting | G | PA | AB | R | H | 2B | 3B | HR | RBI | SB | CS | BB | IBB | SO | BA | OBP | SLG | OPS | HBP | SH | SF | GDP |
| Rios, Alexis | 157 | 688 | 646 | 106 | 213 | 44 | 12 | 14 | 76 | 31 | 11 | 38 | 1 | 101 | .330 | .366 | .500 | .866 | 1 | 0 | 3 | 13 |
| Overbay, Lyle | 153 | 625 | 550 | 59 | 130 | 33 | 0 | 15 | 60 | 3 | 0 | 59 | 2 | 104 | .236 | .312 | .378 | .690 | 6 | 0 | 10 | 21 |
| Scutaro, Marco | 138 | 588 | 518 | 69 | 126 | 24 | 0 | 7 | 45 | 10 | 4 | 52 | 1 | 76 | .243 | .316 | .330 | .646 | 6 | 5 | 7 | 13 |
| Wells, Vernon | 107 | 467 | 435 | 65 | 138 | 28 | 1 | 17 | 87 | 2 | 3 | 21 | 1 | 44 | .317 | .351 | .503 | .855 | 5 | 0 | 6 | 11 |
| Rolen, Scott | 115 | 479 | 403 | 53 | 107 | 29 | 1 | 12 | 49 | 4 | 1 | 52 | 1 | 68 | .266 | .370 | .432 | .801 | 18 | 0 | 6 | 17 |
| Barajas, Rod | 105 | 385 | 357 | 36 | 93 | 19 | 0 | 15 | 60 | 0 | 0 | 16 | 0 | 55 | .261 | .291 | .440 | .731 | 3 | 0 | 9 | 7 |
| Stairs, Matt | 93 | 384 | 335 | 52 | 91 | 15 | 0 | 18 | 59 | 2 | 2 | 40 | 6 | 95 | .272 | .352 | .478 | .829 | 4 | 0 | 5 | 19 |
| Lind, Adam | 87 | 354 | 334 | 35 | 86 | 16 | 7 | 7 | 42 | 3 | 2 | 13 | 1 | 73 | .257 | .288 | .410 | .698 | 3 | 0 | 4 | 11 |
| Inglett, Joe | 92 | 381 | 332 | 50 | 103 | 13 | 8 | 7 | 29 | 12 | 3 | 35 | 2 | 38 | .310 | .378 | .461 | .839 | 2 | 11 | 1 | 3 |
| Eckstein, David | 71 | 311 | 263 | 44 | 68 | 17 | 0 | 1 | 28 | 1 | 0 | 29 | 1 | 25 | .259 | .347 | .335 | .681 | 8 | 8 | 3 | 8 |
| Zaun, Gregg | 72 | 276 | 229 | 24 | 55 | 14 | 1 | 4 | 27 | 1 | 1 | 41 | 0 | 31 | .240 | .357 | .362 | .719 | 1 | 4 | 1 | 5 |
| Hill, Aaron | 53 | 239 | 214 | 27 | 65 | 18 | 0 | 6 | 26 | 4 | 1 | 20 | 0 | 31 | .304 | .366 | .472 | .838 | 1 | 4 | 0 | 6 |
| Wilkerson, Brad | 64 | 236 | 202 | 26 | 45 | 6 | 3 | 1 | 16 | 4 | 6 | 26 | 1 | 54 | .223 | .316 | .297 | .613 | 3 | 2 | 3 | 7 |
| McDonald, John | 65 | 211 | 188 | 18 | 37 | 6 | 0 | 0 | 17 | 3 | 1 | 13 | 0 | 26 | .197 | .246 | .229 | .475 | 0 | 8 | 2 | 6 |
| Stewart, Shannon | 46 | 192 | 165 | 12 | 34 | 4 | 0 | 0 | 14 | 1 | 1 | 20 | 1 | 15 | .206 | .286 | .230 | .517 | 1 | 0 | 6 | 3 |
| Mench, Kevin | 31 | 129 | 111 | 8 | 25 | 13 | 0 | 0 | 15 | 0 | 0 | 14 | 0 | 21 | .225 | .302 | .342 | .645 | 0 | 0 | 4 | 3 |
| Snider, Travis | 22 | 83 | 81 | 4 | 26 | 5 | 0 | 1 | 10 | 0 | 0 | 0 | 0 | 27 | .321 | .313 | .420 | .733 | 0 | 0 | 2 | 1 |
| Thomas, Frank | 16 | 73 | 53 | 13 | 12 | 1 | 0 | 2 | 12 | 0 | 0 | 18 | 0 | 10 | .226 | .425 | .358 | .783 | 1 | 0 | 1 | 1 |
| Bautista, Jose | 13 | 56 | 50 | 3 | 7 | 0 | 0 | 1 | 4 | 1 | 0 | 4 | 0 | 11 | .140 | .204 | .200 | .404 | 0 | 2 | 0 | 1 |
| Thigpen, Curtis | 6 | 18 | 15 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | .133 | .188 | .133 | .321 | 1 | 2 | 0 | 0 |
| Velandia, Jorge | 2 | 12 | 10 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | .100 | .250 | .200 | .450 | 0 | 0 | 0 | 1 |
| Marcum, Shaun | 25 | 7 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | 0 | 0 | 0 | 0 |
| Burnett, A.J. | 34 | 6 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | .000 | .000 | .000 | .000 | 0 | 1 | 0 | 0 |
| McGowan, Dustin | 19 | 6 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | .000 | .000 | .000 | .000 | 0 | 2 | 0 | 0 |
| Diaz, Robinzon | 2 | 4 | 4 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | .500 | .500 | .500 | 1.000 | 0 | 0 | 0 | 0 |
| Halladay, Roy | 33 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | .000 | .000 | .000 | .000 | 0 | 0 | 0 | 0 |
| Litsch, Jesse | 28 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | 0 | 0 | 0 | 0 |
| Coats, Buck | 2 | 4 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .500 | .000 | .500 | 0 | 0 | 0 | 0 |
| Purcey, David | 12 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | 0 | 0 | 0 | 0 |
| Totals | 162 | 6,221 | 5,520 | 705 | 1,466 | 306 | 33 | 128 | 677 | 84 | 36 | 515 | 18 | 918 | .266 | .331 | .403 | .734 | 64 | 49 | 73 | 157 |
| Team Pitching | W | L | S | ERA | G | GS | CG | IP | H | R | ER | HR | BB | IBB | SO | HBP | BF | WHIP | WP | BK | GDP |
| Halladay, Roy | 16 | 9 | 0 | 2.97 | 33 | 33 | 9 | 251 | 222 | 85 | 83 | 21 | 53 | 4 | 230 | 10 | 1,014 | 1.09 | 4 | 0 | 22 |
| Burnett, A.J. | 15 | 8 | 0 | 3.99 | 34 | 34 | 4 | 234 | 184 | 107 | 104 | 30 | 99 | 1 | 214 | 9 | 971 | 1.21 | 12 | 0 | 20 |
| Litsch, Jesse | 11 | 11 | 0 | 3.72 | 28 | 28 | 0 | 183 | 184 | 82 | 76 | 20 | 43 | 0 | 114 | 11 | 765 | 1.24 | 5 | 0 | 20 |
| Marcum, Shaun | 11 | 5 | 0 | 3.26 | 25 | 25 | 3 | 171 | 142 | 65 | 62 | 21 | 67 | 2 | 134 | 3 | 705 | 1.22 | 4 | 0 | 15 |
| McGowan, Dustin | 10 | 8 | 0 | 4.61 | 19 | 19 | 0 | 119 | 135 | 61 | 61 | 9 | 40 | 1 | 92 | 4 | 522 | 1.47 | 5 | 0 | 5 |
| Downs, Scott | 9 | 2 | 2 | 1.78 | 50 | 0 | 0 | 65 | 45 | 13 | 13 | 5 | 13 | 2 | 60 | 1 | 251 | 0.88 | 2 | 0 | 4 |
| Purcey, David | 5 | 4 | 0 | 7.69 | 12 | 12 | 0 | 62 | 79 | 55 | 53 | 14 | 42 | 0 | 51 | 3 | 297 | 1.95 | 6 | 0 | 8 |
| Carlson, Jesse | 2 | 2 | 1 | 2.48 | 43 | 0 | 0 | 54 | 41 | 15 | 15 | 3 | 20 | 1 | 46 | 2 | 220 | 1.12 | 4 | 0 | 5 |
| Tallet, Brian | 3 | 2 | 1 | 2.19 | 40 | 0 | 0 | 53 | 40 | 19 | 13 | 1 | 20 | 1 | 50 | 7 | 227 | 1.13 | 0 | 0 | 2 |
| Ryan, B.J. | 1 | 2 | 44 | 2.36 | 54 | 0 | 0 | 53 | 42 | 16 | 14 | 3 | 22 | 2 | 49 | 1 | 224 | 1.20 | 1 | 0 | 4 |
| Parrish, John | 2 | 4 | 0 | 3.83 | 15 | 6 | 0 | 44 | 46 | 19 | 19 | 3 | 10 | 0 | 18 | 1 | 183 | 1.25 | 1 | 0 | 5 |
| Frasor, Jason | 3 | 3 | 2 | 2.05 | 41 | 0 | 0 | 44 | 19 | 10 | 10 | 5 | 26 | 0 | 32 | 1 | 172 | 1.02 | 1 | 0 | 5 |
| Camp, Shawn | 0 | 1 | 1 | 2.08 | 28 | 0 | 0 | 39 | 31 | 13 | 9 | 3 | 14 | 1 | 29 | 2 | 155 | 1.15 | 0 | 0 | 7 |
| Richmond, Scott | 2 | 2 | 0 | 4.64 | 5 | 5 | 1 | 33 | 37 | 17 | 17 | 3 | 9 | 0 | 22 | 1 | 139 | 1.39 | 0 | 0 | 8 |
| League, Brandon | 2 | 1 | 2 | 2.61 | 25 | 0 | 0 | 31 | 22 | 9 | 9 | 3 | 14 | 0 | 19 | 1 | 124 | 1.16 | 2 | 0 | 6 |
| Wolfe, Brian | 1 | 0 | 0 | 2.18 | 14 | 0 | 0 | 20 | 17 | 5 | 5 | 1 | 4 | 1 | 12 | 0 | 77 | 1.02 | 0 | 0 | 3 |
| Accardo, Jeremy | 1 | 3 | 2 | 11.57 | 12 | 0 | 0 | 9 | 24 | 13 | 12 | 4 | 3 | 0 | 1 | 1 | 53 | 2.89 | 0 | 0 | 1 |
| Benitez, Armando | 0 | 1 | 0 | 3.38 | 5 | 0 | 0 | 5 | 4 | 2 | 2 | 1 | 0 | 0 | 7 | 0 | 20 | 0.75 | 0 | 0 | 0 |
| Wells, Randy | 0 | 0 | 1 | 0.00 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0.00 | 0 | 0 | 0 |
| Totals | 94 | 68 | 56 | 3.52 | 162 | 162 | 17 | 1,476 | 1,314 | 606 | 577 | 150 | 499 | 16 | 1,180 | 58 | 6,120 | 1.23 | 47 | 0 | 140 |
| Catcher | G | GS | INN | PO | A | E | DP | PB | PCT | RF9 | SB | CS | POF | |
| Barajas, Rod | C | 99 | 90 | 818 | 666 | 28 | 4 | 5 | 0 | .994 | 7.64 | 57 | 20 | 0 |
| Zaun, Gregg | C | 69 | 67 | 608 | 526 | 18 | 6 | 2 | 4 | .989 | 8.05 | 37 | 14 | 0 |
| Thigpen, Curtis | C | 6 | 5 | 45 | 32 | 2 | 0 | 0 | 0 | 1.000 | 6.80 | 3 | 2 | 0 |
| Totals | C | 162 | 162 | 1,476 | 1,224 | 48 | 10 | 7 | 4 | .992 | 7.76 | 97 | 36 | 0 |
| 1st Base | G | GS | INN | PO | A | E | DP | PB | PCT | RF9 | SB | CS | POF | |
| Overbay, Lyle | 1B | 153 | 151 | 1,356 | 1,265 | 189 | 5 | 114 | 0 | .997 | 9.65 | 0 | 0 | 0 |
| Bautista, Jose | 1B | 4 | 4 | 36 | 34 | 7 | 0 | 4 | 0 | 1.000 | 10.25 | 0 | 0 | 0 |
| Barajas, Rod | 1B | 5 | 3 | 30 | 28 | 7 | 0 | 1 | 0 | 1.000 | 10.50 | 0 | 0 | 0 |
| Wilkerson, Brad | 1B | 5 | 2 | 29 | 37 | 1 | 1 | 5 | 0 | .974 | 11.79 | 0 | 0 | 0 |
| Scutaro, Marco | 1B | 3 | 2 | 19 | 21 | 1 | 0 | 2 | 0 | 1.000 | 10.42 | 0 | 0 | 0 |
| Diaz, Robinzon | 1B | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1.000 | 18.00 | 0 | 0 | 0 |
| Totals | 1B | 162 | 162 | 1,476 | 1,386 | 206 | 6 | 126 | 0 | .996 | 9.71 | 0 | 0 | 0 |
| 2nd Base | G | GS | INN | PO | A | E | DP | PB | PCT | RF9 | SB | CS | POF | |
| Inglett, Joe | 2B | 62 | 62 | 563 | 131 | 161 | 7 | 39 | 0 | .977 | 4.67 | 0 | 0 | 0 |
| Hill, Aaron | 2B | 53 | 53 | 487 | 91 | 154 | 0 | 29 | 0 | 1.000 | 4.53 | 0 | 0 | 0 |
| Scutaro, Marco | 2B | 39 | 39 | 348 | 88 | 100 | 1 | 23 | 0 | .995 | 4.86 | 0 | 0 | 0 |
| Eckstein, David | 2B | 5 | 5 | 46 | 10 | 14 | 0 | 4 | 0 | 1.000 | 4.70 | 0 | 0 | 0 |
| Bautista, Jose | 2B | 2 | 2 | 18 | 4 | 5 | 0 | 0 | 0 | 1.000 | 4.50 | 0 | 0 | 0 |
| Velandia, Jorge | 2B | 1 | 1 | 9 | 5 | 4 | 0 | 2 | 0 | 1.000 | 9.00 | 0 | 0 | 0 |
| Totals | 2B | 162 | 162 | 1,476 | 329 | 438 | 8 | 97 | 0 | .990 | 4.68 | 0 | 0 | 0 |
| 3rd Base | G | GS | INN | PO | A | E | DP | PB | PCT | RF9 | SB | CS | POF | |
| Rolen, Scott | 3B | 115 | 115 | 1,040 | 82 | 199 | 6 | 18 | 0 | .979 | 2.43 | 0 | 0 | 0 |
| Scutaro, Marco | 3B | 37 | 36 | 332 | 22 | 51 | 1 | 3 | 0 | .986 | 1.98 | 0 | 0 | 0 |
| Inglett, Joe | 3B | 5 | 5 | 44 | 3 | 10 | 0 | 1 | 0 | 1.000 | 2.66 | 0 | 0 | 0 |
| Bautista, Jose | 3B | 4 | 4 | 37 | 4 | 4 | 0 | 0 | 0 | 1.000 | 1.95 | 0 | 0 | 0 |
| McDonald, John | 3B | 2 | 2 | 18 | 1 | 5 | 0 | 0 | 0 | 1.000 | 3.00 | 0 | 0 | 0 |
| Totals | 3B | 162 | 162 | 1,476 | 112 | 269 | 7 | 22 | 0 | .982 | 2.32 | 0 | 0 | 0 |
| Shortstop | G | GS | INN | PO | A | E | DP | PB | PCT | RF9 | SB | CS | POF | |
| Eckstein, David | SS | 57 | 56 | 492 | 85 | 150 | 6 | 35 | 0 | .975 | 4.30 | 0 | 0 | 0 |
| McDonald, John | SS | 57 | 52 | 483 | 77 | 165 | 11 | 45 | 0 | .957 | 4.51 | 0 | 0 | 0 |
| Scutaro, Marco | SS | 53 | 53 | 476 | 69 | 142 | 3 | 26 | 0 | .986 | 3.99 | 0 | 0 | 0 |
| Velandia, Jorge | SS | 1 | 1 | 18 | 3 | 10 | 0 | 2 | 0 | 1.000 | 6.50 | 0 | 0 | 0 |
| Inglett, Joe | SS | 1 | 0 | 2 | 1 | 1 | 0 | 1 | 0 | 1.000 | 9.00 | 0 | 0 | 0 |
| Totals | SS | 162 | 162 | 1,476 | 235 | 468 | 20 | 109 | 0 | .972 | 4.29 | 0 | 0 | 0 |
| Left Field | G | GS | INN | PO | A | E | DP | PB | PCT | RF9 | SB | CS | POF | |
| Lind, Adam | LF | 71 | 71 | 649 | 162 | 8 | 0 | 1 | 0 | 1.000 | 2.36 | 0 | 0 | 0 |
| Stewart, Shannon | LF | 38 | 36 | 320 | 74 | 0 | 0 | 0 | 0 | 1.000 | 2.08 | 0 | 0 | 0 |
| Mench, Kevin | LF | 14 | 14 | 121 | 33 | 1 | 0 | 0 | 0 | 1.000 | 2.53 | 0 | 0 | 0 |
| Wilkerson, Brad | LF | 13 | 13 | 115 | 25 | 0 | 0 | 0 | 0 | 1.000 | 1.96 | 0 | 0 | 0 |
| Snider, Travis | LF | 11 | 11 | 97 | 29 | 0 | 0 | 0 | 0 | 1.000 | 2.69 | 0 | 0 | 0 |
| Stairs, Matt | LF | 10 | 8 | 71 | 14 | 0 | 0 | 0 | 0 | 1.000 | 1.77 | 0 | 0 | 0 |
| Inglett, Joe | LF | 7 | 5 | 63 | 14 | 0 | 0 | 0 | 0 | 1.000 | 2.00 | 0 | 0 | 0 |
| Scutaro, Marco | LF | 3 | 3 | 26 | 4 | 1 | 0 | 0 | 0 | 1.000 | 1.73 | 0 | 0 | 0 |
| Coats, Buck | LF | 2 | 1 | 9 | 3 | 0 | 0 | 0 | 0 | 1.000 | 3.00 | 0 | 0 | 0 |
| Totals | LF | 162 | 162 | 1,476 | 358 | 10 | 0 | 1 | 0 | 1.000 | 2.24 | 0 | 0 | 0 |
| Center Field | G | GS | INN | PO | A | E | DP | PB | PCT | RF9 | SB | CS | POF | |
| Wells, Vernon | CF | 99 | 99 | 895 | 199 | 13 | 4 | 0 | 0 | .981 | 2.13 | 0 | 0 | 0 |
| Rios, Alexis | CF | 60 | 59 | 540 | 130 | 9 | 1 | 1 | 0 | .993 | 2.32 | 0 | 0 | 0 |
| Wilkerson, Brad | CF | 3 | 3 | 27 | 2 | 0 | 0 | 0 | 0 | 1.000 | 0.67 | 0 | 0 | 0 |
| Inglett, Joe | CF | 1 | 1 | 9 | 0 | 0 | 0 | 0 | 0 | .000 | 0.00 | 0 | 0 | 0 |
| Totals | CF | 162 | 162 | 1,476 | 331 | 22 | 5 | 1 | 0 | .986 | 2.15 | 0 | 0 | 0 |
| Right Field | G | GS | INN | PO | A | E | DP | PB | PCT | RF9 | SB | CS | POF | |
| Rios, Alexis | RF | 92 | 92 | 829 | 170 | 10 | 0 | 1 | 0 | 1.000 | 1.95 | 0 | 0 | 0 |
| Wilkerson, Brad | RF | 38 | 37 | 338 | 56 | 0 | 1 | 0 | 0 | .982 | 1.49 | 0 | 0 | 0 |
| Mench, Kevin | RF | 11 | 11 | 108 | 27 | 0 | 0 | 0 | 0 | 1.000 | 2.25 | 0 | 0 | 0 |
| Inglett, Joe | RF | 9 | 9 | 79 | 8 | 0 | 0 | 0 | 0 | 1.000 | 0.91 | 0 | 0 | 0 |
| Snider, Travis | RF | 7 | 7 | 62 | 13 | 0 | 0 | 0 | 0 | 1.000 | 1.89 | 0 | 0 | 0 |
| Stairs, Matt | RF | 6 | 6 | 55 | 9 | 2 | 0 | 0 | 0 | 1.000 | 1.80 | 0 | 0 | 0 |
| Totals | RF | 162 | 162 | 1,476 | 283 | 12 | 1 | 1 | 0 | .997 | 1.80 | 0 | 0 | 0 |
| Pitcher | G | GS | INN | PO | A | E | DP | PB | PCT | RF9 | SB | CS | POF | |
| Halladay, Roy | P | 33 | 33 | 245 | 39 | 24 | 0 | 2 | 0 | 1.000 | 2.31 | 25 | 1 | 1 |
| Burnett, A.J. | P | 34 | 34 | 227 | 32 | 28 | 3 | 1 | 0 | .952 | 2.38 | 15 | 8 | 0 |
| Litsch, Jesse | P | 28 | 28 | 176 | 13 | 21 | 2 | 1 | 0 | .944 | 1.74 | 8 | 4 | 1 |
| Marcum, Shaun | P | 25 | 25 | 165 | 15 | 20 | 0 | 1 | 0 | 1.000 | 1.91 | 2 | 0 | 1 |
| McGowan, Dustin | P | 19 | 19 | 115 | 12 | 11 | 1 | 0 | 0 | .958 | 1.80 | 12 | 5 | 0 |
| Purcey, David | P | 12 | 12 | 60 | 12 | 12 | 0 | 2 | 0 | 1.000 | 3.60 | 8 | 4 | 0 |
| Downs, Scott | P | 50 | 0 | 55 | 9 | 5 | 2 | 0 | 0 | .875 | 2.29 | 4 | 1 | 1 |
| Ryan, B.J. | P | 53 | 0 | 51 | 7 | 4 | 0 | 1 | 0 | 1.000 | 1.94 | 6 | 0 | 0 |
| Carlson, Jesse | P | 42 | 0 | 43 | 11 | 5 | 0 | 0 | 0 | 1.000 | 3.35 | 4 | 1 | 0 |
| Tallet, Brian | P | 40 | 0 | 41 | 6 | 2 | 0 | 0 | 0 | 1.000 | 1.76 | 4 | 3 | 0 |
| Parrish, John | P | 15 | 6 | 41 | 1 | 3 | 0 | 1 | 0 | 1.000 | 0.88 | 2 | 4 | 0 |
| Frasor, Jason | P | 41 | 0 | 34 | 3 | 5 | 0 | 1 | 0 | 1.000 | 2.12 | 2 | 1 | 0 |
| Camp, Shawn | P | 28 | 0 | 33 | 4 | 3 | 0 | 1 | 0 | 1.000 | 1.91 | 1 | 2 | 0 |
| Richmond, Scott | P | 5 | 5 | 32 | 0 | 2 | 0 | 0 | 0 | 1.000 | 0.56 | 1 | 1 | 0 |
| League, Brandon | P | 25 | 0 | 24 | 1 | 3 | 0 | 0 | 0 | 1.000 | 1.50 | 1 | 0 | 1 |
| Wolfe, Brian | P | 14 | 0 | 17 | 2 | 3 | 0 | 0 | 0 | 1.000 | 2.65 | 0 | 1 | 1 |
| Accardo, Jeremy | P | 12 | 0 | 6 | 3 | 0 | 0 | 0 | 0 | 1.000 | 4.50 | 2 | 0 | 0 |
| Benitez, Armando | P | 5 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | .000 | 0.00 | 0 | 0 | 0 |
| Wells, Randy | P | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | 0.00 | 0 | 0 | 0 |
| Totals | P | 162 | 162 | 1,476 | 170 | 151 | 8 | 11 | 0 | .976 | 1.96 | 97 | 36 | 8 |
| Schedule |
| Gm | Date | Opp | W-L | Score | H | HA | E | W-L | Pos | GB | Strk | Own | Opp | Save | |
| 1 | 4/1 | @New York (A) | W | 2-1 | (10) | 10 | 8 | 0 | 1-0 | t-1st | 0.0 | W1 | Halladay/TALLET | Wang/Bruney | |
| 2 | 4/2 | @New York (A) | L | 3-4 | 5 | 7 | 0 | 1-1 | t-3rd | 1.0 | L1 | Burnett/Accardo | MUSSINA | Rivera | |
| 3 | 4/3 | @New York (A) | W | 9-6 | 14 | 12 | 0 | 2-1 | 3rd | 0.5 | W1 | MCGOWAN | Hughes/Traber | League | |
| 4 | 4/4 | Boston | W | 3-0 | 8 | 2 | 1 | 3-1 | 2nd | 0.5 | W2 | MARCUM | Wakefield | Wells | |
| 5 | 4/5 | Boston | W | 5-4 | 10 | 9 | 1 | 4-1 | 1st | +0.5 | W3 | LITSCH | Buchholz | Downs | |
| 6 | 4/6 | Boston | W | 4-3 | 6 | 6 | 0 | 5-1 | 1st | +0.5 | W4 | HALLADAY | Beckett | Accardo | |
| 7 | 4/8 | Oakland | W | 4-0 | 6 | 2 | 0 | 6-1 | 1st | +1.0 | W5 | BURNETT | Gaudin | ||
| 8 | 4/9 | Oakland | W | 2-1 | 7 | 9 | 0 | 7-1 | 1st | +2.0 | W6 | MCGOWAN | Smith | Tallet | |
| 9 | 4/10 | Oakland | W | 9-5 | 12 | 9 | 0 | 8-1 | 1st | +2.0 | W7 | MARCUM | Eveland | Accardo | |
| 10 | 4/11 | @Texas | L | 1-3 | 7 | 10 | 1 | 8-2 | 1st | +2.0 | L1 | Litsch | Padilla/GERMAN | Benoit | |
| 11 | 4/12 | @Texas | W | 3-2 | 8 | 6 | 0 | 9-2 | 1st | +2.0 | W1 | HALLADAY | Mendoza | ||
| 12 | 4/13 | @Texas | W | 6-5 | 10 | 6 | 1 | 10-2 | 1st | +2.0 | W2 | BURNETT | Feldman/Nippert | Ryan | |
| 13 | 4/14 | @Baltimore | W | 10-4 | 9 | 8 | 0 | 11-2 | 1st | +2.0 | W3 | MCGOWAN | Albers/Johnson | Frasor | |
| 14 | 4/15 | @Baltimore | W | 9-7 | (15) | 17 | 14 | 1 | 12-2 | 1st | +3.0 | W4 | Marcum/CARLSON | Trachsel/Aquino | |
| 15 | 4/16 | Texas | W | 4-2 | 11 | 7 | 1 | 13-2 | 1st | +3.0 | W5 | LITSCH | Gabbard | Ryan | |
| 16 | 4/17 | Texas | L | 5-9 | 9 | 14 | 0 | 13-3 | 1st | +2.0 | L1 | Halladay/Accardo | PADILLA | ||
| 17 | 4/18 | Detroit | W | 11-8 | 14 | 9 | 0 | 14-3 | 1st | +2.0 | W1 | Purcey/DOWNS | Rogers | Ryan | |
| 18 | 4/19 | Detroit | L | 0-1 | 5 | 6 | 0 | 14-4 | 1st | +2.0 | L1 | McGowan | BONDERMAN | ||
| 19 | 4/20 | Detroit | L | 8-11 | 12 | 14 | 1 | 14-5 | 1st | +1.0 | L2 | Burnett/Carlson | Robertson/BAUTISTA | Jones | |
| 20 | 4/21 | Detroit | W | 4-0 | 9 | 3 | 0 | 15-5 | 1st | +1.5 | W1 | MARCUM | Galarraga | ||
| 21 | 4/22 | @Tampa Bay | L | 2-5 | 5 | 13 | 1 | 15-6 | 1st | +0.5 | L1 | Litsch | SHIELDS | Percival | |
| 22 | 4/23 | @Tampa Bay | W | 4-2 | 10 | 6 | 0 | 16-6 | 1st | +1.5 | W1 | HALLADAY | Hammel | Ryan | |
| 23 | 4/24 | @Tampa Bay | L | 4-5 | 12 | 8 | 0 | 16-7 | 1st | +0.5 | L1 | McGowan | SONNANSTINE | Wheeler | |
| 24 | 4/25 | @Kansas City | W | 7-2 | 10 | 9 | 1 | 17-7 | 1st | +0.5 | W1 | BURNETT | Greinke | ||
| 25 | 4/26 | @Kansas City | W | 11-2 | 14 | 5 | 0 | 18-7 | 1st | +1.5 | W2 | MARCUM | Hochevar | ||
| 26 | 4/27 | @Kansas City | W | 3-1 | 10 | 5 | 0 | 19-7 | 1st | +2.5 | W3 | LITSCH | Meche | Ryan | |
| 27 | 4/29 | @Boston | L | 4-5 | 9 | 11 | 0 | 19-8 | 1st | +1.5 | L1 | Halladay | LESTER | Papelbon | |
| 28 | 4/30 | @Boston | W | 6-4 | 12 | 11 | 0 | 20-8 | 1st | +2.5 | W1 | McGowan/DOWNS | Matsuzaka/Timlin | Ryan | |
| 29 | 5/1 | @Boston | W | 8-6 | (10) | 10 | 12 | 0 | 21-8 | 1st | +3.5 | W2 | Burnett/ACCARDO | Wakefield/Timlin | Ryan |
| 30 | 5/2 | Chicago (A) | L | 2-3 | (12) | 9 | 10 | 0 | 21-9 | 1st | +2.5 | L1 | Marcum/Accardo | Buehrle/THORNTON | Jenks |
| 31 | 5/3 | Chicago (A) | L | 2-5 | 8 | 11 | 0 | 21-10 | 1st | +1.5 | L2 | Litsch | DANKS | Jenks | |
| 32 | 5/4 | Chicago (A) | L | 3-4 | 7 | 7 | 0 | 21-11 | 1st | +1.5 | L3 | Halladay | CONTRERAS | Jenks | |
| 33 | 5/5 | Chicago (A) | W | 6-4 | 12 | 10 | 0 | 22-11 | 1st | +2.0 | W1 | MCGOWAN | Vazquez | Ryan | |
| 34 | 5/6 | Tampa Bay | W | 4-2 | 5 | 8 | 0 | 23-11 | 1st | +2.5 | W2 | BURNETT | Sonnanstine | Ryan | |
| 35 | 5/7 | Tampa Bay | W | 3-1 | 6 | 6 | 0 | 24-11 | 1st | +2.5 | W3 | MARCUM | Garza | Ryan | |
| 36 | 5/8 | Tampa Bay | W | 2-1 | 6 | 4 | 0 | 25-11 | 1st | +3.5 | W4 | LITSCH | Jackson | Carlson | |
| 37 | 5/9 | @Cleveland | W | 4-3 | 5 | 6 | 0 | 26-11 | 1st | +3.5 | W5 | HALLADAY | Sabathia | Ryan | |
| 38 | 5/10 | @Cleveland | W | 4-2 | 9 | 10 | 0 | 27-11 | 1st | +3.5 | W6 | MCGOWAN | Laffey | Ryan | |
| 39 | 5/12 | @Cleveland | W | 5-3 | 11 | 5 | 0 | 28-11 | 1st | +2.5 | W7 | BURNETT | Carmona | Ryan | |
| 40 | 5/12 | @Cleveland | L | 1-5 | (19) | 13 | 8 | 0 | 28-12 | 1st | +2.5 | L1 | Marcum/Carlson | Lee/BRESLOW | |
| 41 | 5/13 | @Minnesota | L | 1-2 | 5 | 7 | 0 | 28-13 | 1st | +1.5 | L2 | Litsch/Benitez | Slowey/REYES | ||
| 42 | 5/14 | @Minnesota | L | 0-3 | 6 | 8 | 0 | 28-14 | 1st | +1.5 | L3 | Halladay | BONSER | Nathan | |
| 43 | 5/15 | @Minnesota | L | 4-5 | 9 | 9 | 0 | 28-15 | 1st | +1.0 | L4 | McGowan | PERKINS | Nathan | |
| 44 | 5/16 | @Philadelphia | L | 2-8 | 7 | 12 | 0 | 28-16 | 1st | +0.5 | L5 | Purcey | MOYER | ||
| 45 | 5/17 | @Philadelphia | W | 7-2 | 11 | 4 | 3 | 29-16 | t-1st | 0.0 | W1 | BURNETT | Eaton | ||
| 46 | 5/18 | @Philadelphia | W | 8-1 | 10 | 7 | 0 | 30-16 | t-1st | 0.0 | W2 | MARCUM | Kendrick | ||
| 47 | 5/20 | Los Angeles (A) | L | 5-9 | 8 | 9 | 0 | 30-17 | 2nd | 1.5 | L1 | McGowan | LACKEY | ||
| 48 | 5/21 | Los Angeles (A) | L | 1-3 | 7 | 7 | 0 | 30-18 | 2nd | 2.5 | L2 | Marcum | GARLAND | Rodriguez | |
| 49 | 5/22 | Los Angeles (A) | W | 2-1 | 5 | 4 | 0 | 31-18 | 2nd | 2.5 | W1 | BURNETT | Santana | Ryan | |
| 50 | 5/23 | Kansas City | W | 2-1 | 6 | 4 | 1 | 32-18 | 2nd | 2.5 | W2 | HALLADAY | Greinke/Yabuta | Ryan | |
| 51 | 5/24 | Kansas City | W | 1-0 | 3 | 4 | 0 | 33-18 | 2nd | 1.5 | W3 | LITSCH | Hochevar | Ryan | |
| 52 | 5/25 | Kansas City | W | 4-2 | 6 | 7 | 0 | 34-18 | 2nd | 1.5 | W4 | MCGOWAN | Meche | Downs | |
| 53 | 5/26 | Kansas City | W | 5-4 | 6 | 9 | 1 | 35-18 | 2nd | 1.5 | W5 | Marcum/CARLSON | Tomko/Soria | ||
| 54 | 5/27 | @Oakland | W | 5-3 | 7 | 8 | 0 | 36-18 | 2nd | 1.5 | W6 | Burnett/FRASOR | Smith/Street | Ryan | |
| 55 | 5/28 | @Oakland | W | 4-2 | 10 | 4 | 0 | 37-18 | 2nd | 0.5 | W7 | HALLADAY | Harden | Ryan | |
| 56 | 5/29 | @Oakland | L | 3-4 | 8 | 5 | 0 | 37-19 | 2nd | 1.0 | L1 | Litsch | Eveland/BRADEN | Street | |
| 57 | 5/30 | @Los Angeles (A) | W | 3-1 | 4 | 10 | 0 | 38-19 | 2nd | 1.0 | W1 | MCGOWAN | Weaver | Ryan | |
| 58 | 5/31 | @Los Angeles (A) | W | 10-3 | 13 | 6 | 0 | 39-19 | 2nd | 1.0 | W2 | MARCUM | Lackey | ||
| 59 | 6/1 | @Los Angeles (A) | W | 5-1 | (11) | 7 | 5 | 0 | 40-19 | 2nd | 1.0 | W3 | Burnett/DOWNS | Garland/Shields | |
| 60 | 6/3 | @New York (A) | L | 1-8 | 6 | 9 | 1 | 40-20 | 2nd | 0.5 | L1 | Halladay | CHAMBERLAIN | ||
| 61 | 6/4 | @New York (A) | W | 2-0 | 8 | 7 | 0 | 41-20 | 2nd | 0.5 | W1 | LITSCH | Mussina | Ryan | |
| 62 | 6/5 | @New York (A) | L | 2-4 | 6 | 8 | 0 | 41-21 | 2nd | 0.5 | L1 | McGowan | WANG | Rivera | |
| 63 | 6/6 | Baltimore | L | 3-4 | 8 | 9 | 1 | 41-22 | 2nd | 0.5 | L2 | Marcum | BURRES | Sherrill | |
| 64 | 6/7 | Baltimore | L | 4-5 | 9 | 8 | 0 | 41-23 | 2nd | 1.5 | L3 | Burnett | GUTHRIE | Sherrill | |
| 65 | 6/8 | Baltimore | W | 4-0 | 7 | 7 | 0 | 42-23 | 2nd | 1.5 | W1 | HALLADAY | Liz | ||
| 66 | 6/9 | Seattle | L | 4-8 | 9 | 14 | 1 | 42-24 | 2nd | 2.0 | L1 | Litsch | WASHBURN | ||
| 67 | 6/10 | Seattle | L | 4-8 | 13 | 10 | 1 | 42-25 | 2nd | 3.0 | L2 | McGowan | SILVA | ||
| 68 | 6/11 | Seattle | L | 2-12 | 9 | 17 | 0 | 42-26 | 2nd | 3.0 | L3 | Marcum | HERNANDEZ | ||
| 69 | 6/13 | Chicago (N) | W | 6-5 | 8 | 7 | 1 | 43-26 | 2nd | 3.5 | W1 | Burnett/DOWNS | Gallagher/Wood | ||
| 70 | 6/14 | Chicago (N) | W | 14-2 | 12 | 6 | 0 | 44-26 | 2nd | 3.5 | W2 | HALLADAY | Marquis | ||
| 71 | 6/15 | Chicago (N) | W | 7-1 | 7 | 9 | 1 | 45-26 | 2nd | 3.5 | W3 | LITSCH | Lilly | ||
| 72 | 6/17 | @Milwaukee | W | 9-7 | 18 | 13 | 1 | 46-26 | 2nd | 2.0 | W4 | MCGOWAN | Parra | Ryan | |
| 73 | 6/18 | @Milwaukee | L | 2-3 | (12) | 11 | 9 | 1 | 46-27 | 2nd | 3.0 | L1 | Marcum/Frasor | Sheets/VILLANUEVA | |
| 74 | 6/19 | @Milwaukee | L | 3-7 | 10 | 10 | 0 | 46-28 | 2nd | 3.5 | L2 | Burnett | BUSH | ||
| 75 | 6/20 | @Pittsburgh | L | 1-2 | (10) | 6 | 10 | 0 | 46-29 | 2nd | 4.5 | L3 | Halladay/Downs | Duke/GRABOW | |
| 76 | 6/21 | @Pittsburgh | L | 3-5 | 5 | 11 | 0 | 46-30 | 2nd | 5.5 | L4 | Litsch | MAHOLM | Capps | |
| 77 | 6/22 | @Pittsburgh | W | 9-2 | 13 | 7 | 0 | 47-30 | 2nd | 4.5 | W1 | MCGOWAN | Snell | ||
| 78 | 6/24 | Cincinnati | W | 9-3 | 12 | 5 | 0 | 48-30 | 2nd | 5.0 | W2 | BURNETT | Arroyo | ||
| 79 | 6/25 | Cincinnati | W | 4-2 | 11 | 9 | 0 | 49-30 | 2nd | 5.0 | W3 | HALLADAY | Harang | Ryan | |
| 80 | 6/26 | Cincinnati | L | 5-9 | 8 | 12 | 0 | 49-31 | 2nd | 5.5 | L1 | Litsch | VOLQUEZ | ||
| 81 | 6/27 | Atlanta | L | 2-3 | 8 | 6 | 0 | 49-32 | 2nd | 5.5 | L2 | McGowan | JURRJENS | Gonzalez | |
| 82 | 6/28 | Atlanta | W | 3-1 | 6 | 6 | 1 | 50-32 | 2nd | 5.5 | W1 | PARRISH | Hudson | Ryan | |
| 83 | 6/29 | Atlanta | L | 4-7 | 9 | 7 | 2 | 50-33 | 2nd | 5.5 | L1 | Burnett | REYES | Gonzalez | |
| 84 | 6/30 | @Seattle | W | 10-1 | 15 | 4 | 0 | 51-33 | 2nd | 5.5 | W1 | HALLADAY | Dickey | ||
| 85 | 7/1 | @Seattle | L | 5-7 | 12 | 13 | 2 | 51-34 | 2nd | 6.5 | L1 | Litsch/Tallet | Rowland-Smith/JIMENEZ | Morrow | |
| 86 | 7/2 | @Seattle | W | 7-2 | 12 | 7 | 1 | 52-34 | 2nd | 5.5 | W1 | MCGOWAN | Washburn | ||
| 87 | 7/4 | @Los Angeles (A) | W | 7-1 | 13 | 6 | 0 | 53-34 | 2nd | 4.0 | W2 | BURNETT | Weaver | ||
| 88 | 7/5 | @Los Angeles (A) | W | 3-1 | (10) | 11 | 10 | 0 | 54-34 | 2nd | 4.0 | W3 | Halladay/TALLET | Lackey/Arredondo | Ryan |
| 89 | 7/6 | @Los Angeles (A) | L | 0-6 | 3 | 10 | 0 | 54-35 | 2nd | 5.0 | L1 | Litsch | GARLAND | ||
| 90 | 7/8 | Baltimore | L | 3-4 | 8 | 8 | 0 | 54-36 | 2nd | 6.5 | L2 | McGowan | CABRERA | Sherrill | |
| 91 | 7/9 | Baltimore | W | 7-6 | 11 | 8 | 1 | 55-36 | 2nd | 5.5 | W1 | Burnett/DOWNS | Olson/Sarfate | Ryan | |
| 92 | 7/10 | Baltimore | L | 0-4 | 8 | 8 | 0 | 55-37 | 2nd | 6.0 | L1 | Parrish | GUTHRIE | ||
| 93 | 7/11 | New York (A) | W | 6-5 | 17 | 10 | 1 | 56-37 | 2nd | 5.0 | W1 | Halladay/DOWNS | Chamberlain/Farnsworth | ||
| 94 | 7/12 | New York (A) | L | 5-9 | 10 | 13 | 0 | 56-38 | 2nd | 6.0 | L1 | Litsch | RASNER | ||
| 95 | 7/13 | New York (A) | W | 4-0 | 10 | 3 | 0 | 57-38 | 2nd | 6.0 | W1 | BURNETT | Pettitte | ||
| 96 | 7/18 | @Tampa Bay | W | 4-2 | 9 | 5 | 0 | 58-38 | 2nd | 6.0 | W2 | BURNETT | Shields | Ryan | |
| 97 | 7/19 | @Tampa Bay | W | 6-2 | 11 | 10 | 0 | 59-38 | 2nd | 5.0 | W3 | HALLADAY | Garza | ||
| 98 | 7/20 | @Tampa Bay | L | 4-11 | 9 | 12 | 0 | 59-39 | 2nd | 6.0 | L1 | Parrish | JACKSON | ||
| 99 | 7/21 | @Baltimore | L | 4-5 | 9 | 12 | 0 | 59-40 | 2nd | 6.0 | L2 | Litsch/Ryan | Liz/CABRERA | ||
| 100 | 7/22 | @Baltimore | L | 2-3 | 8 | 12 | 1 | 59-41 | 2nd | 7.0 | L3 | Marcum/Frasor | Olson/BIERD | ||
| 101 | 7/23 | @Baltimore | W | 4-2 | 7 | 10 | 1 | 60-41 | 2nd | 6.0 | W1 | BURNETT | Guthrie | Ryan | |
| 102 | 7/24 | @Baltimore | L | 8-9 | (14) | 15 | 14 | 2 | 60-42 | 2nd | 6.5 | L1 | Halladay/Frasor | Cabrera/JOHNSON | |
| 103 | 7/25 | Seattle | W | 2-1 | 7 | 4 | 0 | 61-42 | 2nd | 6.5 | W1 | Parrish/DOWNS | Batista/Morrow | ||
| 104 | 7/26 | Seattle | W | 6-5 | 10 | 9 | 0 | 62-42 | 2nd | 5.5 | W2 | PURCEY | Dickey | Ryan | |
| 105 | 7/27 | Seattle | W | 5-1 | 12 | 5 | 0 | 63-42 | 2nd | 4.5 | W3 | MARCUM | Washburn | ||
| 106 | 7/28 | Tampa Bay | L | 0-8 | 5 | 10 | 1 | 63-43 | 2nd | 4.5 | L1 | Burnett | SHIELDS | ||
| 107 | 7/29 | Tampa Bay | L | 1-4 | 7 | 10 | 0 | 63-44 | 2nd | 4.5 | L2 | Halladay | GARZA | Hammel | |
| 108 | 7/30 | Tampa Bay | W | 4-3 | 7 | 10 | 1 | 64-44 | 2nd | 4.5 | W1 | RICHMOND | Jackson | Ryan | |
| 109 | 8/1 | @Texas | W | 6-4 | (10) | 7 | 8 | 0 | 65-44 | 2nd | 4.5 | W2 | Marcum/FRASOR | Hunter/Francisco | Ryan |
| 110 | 8/2 | @Texas | L | 2-6 | 5 | 7 | 0 | 65-45 | 2nd | 5.5 | L1 | Burnett | FELDMAN | ||
| 111 | 8/3 | @Texas | L | 5-6 | (14) | 9 | 15 | 1 | 65-46 | 2nd | 6.5 | L2 | Purcey/Parrish | Mendoza/NIPPERT | |
| 112 | 8/4 | Oakland | W | 9-0 | 13 | 5 | 0 | 66-46 | 2nd | 5.5 | W1 | HALLADAY | Gallagher | ||
| 113 | 8/5 | Oakland | L | 0-4 | 3 | 8 | 3 | 66-47 | 2nd | 6.5 | L1 | Richmond | SMITH | ||
| 114 | 8/6 | Oakland | L | 0-3 | 5 | 6 | 0 | 66-48 | 2nd | 6.5 | L2 | Marcum | GONZALEZ | Ziegler | |
| 115 | 8/7 | Oakland | W | 3-1 | 9 | 3 | 0 | 67-48 | 2nd | 6.0 | W1 | BURNETT | Duchscherer | Ryan | |
| 116 | 8/8 | Cleveland | W | 7-6 | 13 | 8 | 0 | 68-48 | 2nd | 6.0 | W2 | Purcey/DOWNS | Reyes/Kobayashi | ||
| 117 | 8/9 | Cleveland | W | 3-2 | 5 | 8 | 1 | 69-48 | 2nd | 6.0 | W3 | HALLADAY | Byrd | Ryan | |
| 118 | 8/10 | Cleveland | W | 13-4 | 13 | 6 | 1 | 70-48 | 2nd | 5.0 | W4 | RICHMOND | Lee | ||
| 119 | 8/11 | @Detroit | W | 3-1 | (10) | 9 | 6 | 0 | 71-48 | 2nd | 5.0 | W5 | Marcum/RYAN | Verlander/Zumaya | League |
| 120 | 8/12 | @Detroit | L | 3-5 | (10) | 9 | 7 | 0 | 71-49 | 2nd | 6.0 | L1 | Burnett/Downs | Miner/DOLSI | |
| 121 | 8/13 | @Detroit | W | 6-2 | 13 | 7 | 0 | 72-49 | 2nd | 6.0 | W1 | PURCEY | Rogers | ||
| 122 | 8/14 | @Detroit | W | 7-3 | 10 | 9 | 0 | 73-49 | 2nd | 5.0 | W2 | LITSCH | Galarraga | Camp | |
| 123 | 8/16 | @Boston | L | 3-4 | 9 | 8 | 1 | 73-50 | 2nd | 6.0 | L1 | Halladay | Byrd/MASTERSON | Papelbon | |
| 124 | 8/17 | @Boston | L | 3-4 | (10) | 12 | 9 | 0 | 73-51 | 2nd | 7.0 | L2 | Marcum/League | Beckett/LOPEZ | |
| 125 | 8/19 | New York (A) | W | 4-3 | (11) | 9 | 9 | 1 | 74-51 | 2nd | 7.5 | W1 | Burnett/LEAGUE | Rasner/Britton | |
| 126 | 8/20 | New York (A) | W | 6-3 | 11 | 7 | 0 | 75-51 | 2nd | 6.5 | W2 | PURCEY | Pettitte | Ryan | |
| 127 | 8/21 | New York (A) | L | 0-3 | 10 | 8 | 0 | 75-52 | 2nd | 7.0 | L1 | Halladay | PONSON | Rivera | |
| 128 | 8/22 | Boston | W | 4-1 | 5 | 4 | 0 | 76-52 | 2nd | 6.0 | W1 | MARCUM | Byrd | Ryan | |
| 129 | 8/23 | Boston | L | 2-3 | (12) | 10 | 10 | 2 | 76-53 | 2nd | 7.0 | L1 | Litsch/Tallet | Lester/DELCARMEN | Papelbon |
| 130 | 8/24 | Boston | W | 3-2 | 7 | 5 | 0 | 77-53 | 2nd | 6.0 | W1 | Burnett/FRASOR | Matsuzaka/Timlin | Ryan | |
| 131 | 8/26 | @Tampa Bay | L | 3-4 | 10 | 8 | 0 | 77-54 | 2nd | 7.0 | L1 | Halladay/Camp | Shields/WHEELER | Balfour | |
| 132 | 8/27 | @Tampa Bay | L | 3-4 | 9 | 7 | 1 | 77-55 | 2nd | 8.0 | L2 | Purcey | GARZA | Wheeler | |
| 133 | 8/28 | @Tampa Bay | L | 1-8 | 7 | 8 | 3 | 77-56 | 2nd | 9.0 | L3 | Litsch | JACKSON | ||
| 134 | 8/29 | @New York (A) | W | 3-1 | 4 | 4 | 0 | 78-56 | 2nd | 8.0 | W1 | BURNETT | Pavano | Ryan | |
| 135 | 8/30 | @New York (A) | L | 2-7 | 9 | 13 | 0 | 78-57 | 2nd | 8.0 | L1 | Parrish | RASNER | ||
| 136 | 8/31 | @New York (A) | W | 4-3 | 11 | 6 | 0 | 79-57 | 2nd | 7.0 | W1 | HALLADAY | Pettitte | Ryan | |
| 137 | 9/2 | Minnesota | L | 0-7 | 4 | 9 | 2 | 79-58 | 2nd | 7.5 | L1 | Purcey | PERKINS | ||
| 138 | 9/3 | Minnesota | W | 6-1 | 8 | 4 | 0 | 80-58 | 2nd | 7.5 | W1 | BURNETT | Blackburn | ||
| 139 | 9/4 | Minnesota | W | 6-2 | 12 | 8 | 1 | 81-58 | 2nd | 7.0 | W2 | Litsch/WOLFE | Slowey/Humber | ||
| 140 | 9/5 | Tampa Bay | W | 6-5 | 7 | 13 | 0 | 82-58 | 2nd | 7.0 | W3 | HALLADAY | Sonnanstine | Ryan | |
| 141 | 9/6 | Tampa Bay | L | 1-6 | 5 | 8 | 1 | 82-59 | 2nd | 8.0 | L1 | Marcum | SHIELDS | ||
| 142 | 9/7 | Tampa Bay | W | 7-6 | 11 | 11 | 2 | 83-59 | 2nd | 8.0 | W1 | PURCEY | Garza | Ryan | |
| 143 | 9/9 | @Chicago (A) | L | 0-2 | 5 | 3 | 0 | 83-60 | 2nd | 9.0 | L1 | Burnett | VAZQUEZ | Jenks | |
| 144 | 9/9 | @Chicago (A) | L | 1-2 | 6 | 5 | 0 | 83-61 | 2nd | 9.0 | L2 | Litsch | RICHARD | Jenks | |
| 145 | 9/10 | @Chicago (A) | W | 4-3 | (12) | 13 | 6 | 1 | 84-61 | 2nd | 9.0 | W1 | Halladay/LEAGUE | Buehrle/Logan | Ryan |
| 146 | 9/11 | @Chicago (A) | W | 8-5 | 16 | 14 | 0 | 85-61 | 2nd | 8.5 | W2 | MARCUM | Floyd | Frasor | |
| 147 | 9/12 | @Boston | L | 5-9 | 12 | 8 | 0 | 85-62 | 2nd | 9.5 | L1 | Purcey | WAKEFIELD | ||
| 148 | 9/13 | @Boston | L | 4-7 | 10 | 11 | 1 | 85-63 | 2nd | 9.5 | L2 | Burnett | BYRD | Papelbon | |
| 149 | 9/13 | @Boston | W | 12-4 | 17 | 11 | 1 | 86-63 | 2nd | 9.5 | W1 | LITSCH | Colon | ||
| 150 | 9/14 | @Boston | L | 0-2 | 3 | 6 | 0 | 86-64 | 2nd | 10.5 | L1 | Halladay | LESTER | Papelbon | |
| 151 | 9/16 | Baltimore | W | 7-0 | 11 | 4 | 0 | 87-64 | 2nd | 11.0 | W1 | MARCUM | Waters | ||
| 152 | 9/17 | Baltimore | W | 7-2 | 8 | 6 | 1 | 88-64 | 2nd | 10.0 | W2 | PURCEY | Bass | ||
| 153 | 9/18 | Baltimore | W | 3-1 | 8 | 4 | 1 | 89-64 | 2nd | 9.5 | W3 | LITSCH | Olson | Ryan | |
| 154 | 9/19 | Boston | L | 3-7 | 9 | 10 | 0 | 89-65 | 2nd | 10.5 | L1 | Burnett | BYRD | ||
| 155 | 9/20 | Boston | L | 2-6 | 9 | 13 | 0 | 89-66 | 2nd | 11.5 | L2 | Halladay | LESTER | ||
| 156 | 9/21 | Boston | L | 0-2 | 8 | 9 | 0 | 89-67 | 2nd | 12.5 | L3 | Richmond | MATSUZAKA | Papelbon | |
| 157 | 9/23 | New York (A) | W | 2-1 | 5 | 5 | 1 | 90-67 | 2nd | 13.0 | W1 | Litsch/DOWNS | Mussina | Ryan | |
| 158 | 9/24 | New York (A) | L | 9-13 | 14 | 14 | 1 | 90-68 | 2nd | 14.0 | L1 | Burnett/Ryan | Hughes/SANCHEZ | ||
| 159 | 9/25 | New York (A) | W | 7-0 | 7 | 6 | 0 | 91-68 | 2nd | 14.0 | W1 | HALLADAY | Pavano | ||
| 160 | 9/26 | @Baltimore | W | 8-6 | 13 | 13 | 0 | 92-68 | 2nd | 13.0 | W2 | Richmond/TALLET | Waters/Burres | Ryan | |
| 161 | 9/27 | @Baltimore | W | 3-2 | 6 | 6 | 1 | 93-68 | 2nd | 12.5 | W3 | PARRISH | Bass | Ryan | |
| 162 | 9/28 | @Baltimore | W | 13-2 | 18 | 4 | 1 | 94-68 | 2nd | 11.0 | W4 | LITSCH | Guthrie |